Genomics England

There is a more recent signed-off version of this panel

Relevant disorders: PMG, MPGN, Primary Membranoproliferative Glomerulonephritis, Primary membranoproliferative glomerulonephritis, R197

Signed off date: 16 Oct 2020

Panel types: Rare Disease 100K, GMS Rare Disease Virtual, GMS Rare Disease, GMS signed-off

8 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	C3	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Loss-of-function variants DO NOT cause this phenotype	N/A
Green	CFB	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Loss-of-function variants DO NOT cause this phenotype	for-review
Green	CFH	BIALLELIC, autosomal or pseudoautosomal	N/A	N/A
Green	CFHR1	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	N/A	currently-ngs-unreportable
Green	CFHR2	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	N/A	currently-ngs-unreportable
Green	CFHR5	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	N/A	currently-ngs-unreportable
Green	CFI	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	N/A	for-review
Green	DGKE	BIALLELIC, autosomal or pseudoautosomal	N/A	N/A