Genomics England

Genes and Entities

Sarcoma susceptibility (Version: )

This cancer panel will be applied as appropriate in the GMS cancer pipeline and is not requestable separately.

Signed off date: 18 Feb 2020

Panel types: GMS Cancer Germline Virtual, GMS signed-off

See this panel in PanelApp

8 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	EXT1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	EXT2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MTAP	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	NF1	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	RECQL4	BIALLELIC, autosomal or pseudoautosomal	N/A	N/A
Green	SQSTM1	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	T	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	TP53	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A