Genomics England

Genes and Entities

Inherited ovarian cancer (without breast cancer) (Version: )

There is a more recent signed-off version of this panel

Relevant disorders: Familial ovarian cancer, R207

Signed off date: 30 Nov 2022

Panel types: Rare Disease 100K, GMS Rare Disease, GMS signed-off

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9 green entities

Entity rating	Entity	Mode of inheritance	Mode of pathogenicity	Tags
Green	BRCA1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	Q2_22_MOI, Q2_22_expert_review
Green	BRCA2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	BRIP1	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	N/A	N/A
Green	MLH1	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MSH2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	MSH6	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	PALB2	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	RAD51C	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A
Green	RAD51D	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	N/A	N/A