Genomics England
GMS Panels
Panels
Genes and Entities

DNASE2

deoxyribonuclease 2, lysosomal
OMIM: 126350
PanelMode of inheritanceDetails
1 panel
Green
in Primary immunodeficiency or monogenic inflammatory bowel disease
R-numbers: R15
Signed-off version 3.1
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Glomerulonephritis, arthropathy, vasculitis, Autoinflammatory Disorders, multisystem autoinflammatory syndrome, severe neonatal anemia, membranoproliferative glomerulonephritis, liver fibrosis, deforming arthropathy, SLE